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The Value of Basic and Translational Research

basic research
The study of mitochondria, shown here in this electron micrograph, could lead to important clues about MacTel.

Basic research is the foundation of medical discovery.  Through it, we learn key information about the fundamental biological, molecular, and chemical processes of life.

Translational research is the process of taking a discovery from the laboratory into the clinic, where it can ultimately help people.  Often referred to as “bench to bedside” research, it encompasses several stages.  These include testing hypotheses using disease models in the laboratory, bringing new therapies to the clinic to determine their effectiveness in patients, and evaluating if new therapies lead to improved public health.

The mission of the Lowy Medical Research Institute is to improve the lives of people affected by MacTel by developing new therapies to treat or cure MacTel.  Realizing that mission requires us to engage in both basic and translational research.  LMRI supports basic research to learn more about the fundamental biology behind changes that occur in a MacTel eye.  LMRI also supports translational research, from preclinical studies to clinical trials.

At the Lowy Medical Research Institute, basic and translational research are tightly interconnected.  All of the basic science LMRI supports is directly related to MacTel.  The LMRI researchers who do basic research also have ongoing translational research projects.  Open lines of communication between scientists and clinicians speed the pace of discovery and translation to the clinic.

The LMRI research program is designed to help people with MacTel.  However, its discoveries will reach beyond the MacTel community.  The basic research program contributes to the fundamental knowledge of the eye, and could lead to new therapies or new ways of thinking about other forms of vision disease.

 

United Kingdom
Moorfields Eye Hospital

London, United Kingdom
Cathy Egan, MD

Emily Magnus
Tel: 020 7566 2117
Email:Emily.Magnus@moorfields.nhs.uk

Oxford Eye Hospital

Headington, Oxford
Peter Charbel Issa MD

Alexina Fantano
Tel: 01865 231053

 

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United States

California

Scripps Research Institute

La Jolla, CA USA
Martin Friedlander, MD, PhD

Jennifer Trombley, RN
Tel: 858-554-6678
Email: Trombley.jennifer@scrippshealth.org

Jules Stein Eye Institute, UCLA

Los Angeles, CA USA
Jean-Pierre Hubschman, MD

Veronika Sadykov
Tel: 310-794-5596
Email: Sadykov@jsei.ucla.edu

Mary Crowley
Tel: 310-267-5278 Email:
Email: MECrowley@mednet.ucla.edu

University of California – San Francisco

UCSF Department of Ophthalmology
San Fransciso, CA USA
Jacque Duncan, MD

Arshia Mian
Tel: 415-476-0444
Email: arshia.mian@ucsf.edu

Byers Eye Institute – Stanford University

Palo Alto, California
Diana Do, MD

Lisa Greer
Tel: 650-725-9184
Email: lgreer7@stanford.edu

Colorado

Retina Consultants of Southern Colorado

Colorado Springs, CO
Ryan Rich, MD

Sarah Roberts
Tel: 719-473-9595 ext. 134
Email: sroberts@coloradoretina.com

Brad Lovelace
Email: bradlovelace@coloradoretina.com

Florida

Bascom Palmer Eye Institute, University of Miami

Miami, FL USA
Philip Rosenfeld, MD

Cristina Lage-Rodriguez
Tel: 305-326-6117
Email: clage@med.miami.edu

Georgia

Emory University

Atlanta, GA
Jiong Yan, MD

Jayne Brown
Tel: 404-778-4430
Email: jmbrown@emory.edu

Illinois

Northwestern University

Evanston, IL
Amani Fawzi, MD

Nicole Seddon
Tel: 312.695-0252
Email: nreinhol@nm.org

Louisiana

Retina Associates New Orleans

New Orleans, LA USA
Stanislav A. Zhuk, MD

Corey Marvel
Tel: 504-456-9061 ext 1111
Email: cmarvel@retinaassociates.org

Melinda Mitchell
Email: Melinda.mitchell@retinaassociates.org

Maryland

Cumberland Valley Retina Consultants

Hagerstown, MD 21740
David Warrow, MD

Paula Smith
Tel: 301-665-1712
Email: paulas@retinacare.net

Massachusetts

Massachusetts Eye and Ear Infirmary

Boston, MA USA
Joan Miller, MD

Patricia Houlihan
Tel: 617-573-3646
Email: patricia_houlihan@meei.harvard.edu

New England Retina Consultants

Springfield, MA. 01107
David LaLLY, MD

Leah Persky
Tel: 413-788-6044
Email: persky.leah@gmail.com

Michigan

University of Michigan, Kellogg Eye Center

Ann Arbor, MI USA
Grant Comer, MD

Pam Campbell
Tel: 734-936-0138
Email: pamtitus@med.umich.edu

Associated Retinal Consultants – Royal Oak

Royal Oak, MI
Sandeep Randhawa, MD

Kendra Mellert
Tel: 248-288-9132 ext. 1313
E-mail: kmellert@arcpc.net

Associated Retinal Consultants – Grand Rapids

Grand Rapids, MI
V. Raphaelian, M.D.

Deb Markus
Email: dmarkus@arcpc.net

Associated Retinal Consultants – Traverse City

Traverse City, MI
Scott Sneed, MD

Serena Neal
Email: sneal@arcpc.net

Minnesota

Mayo Clinic

Rochester, MN
Sophie Bakri, MD

Heidi Rubin
Email: Rubin.heidi@mayo.edu

Nevada

Sierra Eye Associates

Reno, NV
Arshad Khanani, MD

Deanna Dorman
Tel: 775-329-0286 x 141
Email:ddorman@sierraeyeassociates.com

New Jersey

Retina Center of New Jersey

Bloomfield, NJ
Patrick Higgins, MD

Diane Deininger
Tel: 973-707-5632
Email: ddeininger@retinacenternj.com

Susan Anderson
Tel: 973-707-5632
Email: sanderson@retinacenternj.com

New York

Vitreous, Retina, Macula Consultants of New York

New York, NY USA
Lawrence A. Yannuzzi, MD

Renata Salgado
Tel: 212-452-6965
Email: rsalgado@vrmny.com

The New York Eye and Ear Infirmary

New York, NY USA
Richard Rosen, MD

Meliza Unson
Tel: 212-979-4672
Email: munson@nyee.edu

University of Rochester

Rochester, NY USA
Mina Chung, MD

Lisa Latchney
Tel: 585-273-2742
Email: Lisa_latchney@urmc.rochester.edu

Ohio

Retina Associates of Cleveland, Inc.

Cleveland, OH USA
Lawrence Singerman, MD

Diane Weiss
Tel: 216-831-5704 Ext. 244
Email: dew@retina-assoc.com

Cincinnati Eye Institute

Cincinnati, OH USA
Daniel Miller, MD

Megan Kingdon
Tel: 513-569-3669
Email: mkingdon@cincinnatieye.com

Oregon

Retina Northwest

Portland, OR
Michael Lee, MD

Pualani Smith

Tel: 971-865-2780
Email: psmith@retinanorthwest.com

Pennsylvania

Scheie Eye Institute

Philadelphia, PA USA
Alexander Brucker, MD

Sheri Drossner
Tel: 215-662-8177
Email: Sheri.Grand@uphs.upenn.edu

Texas

Retina Research Center

Austin, TX USA
Chirag Jhaveri, MD
Brian Berger, MD

Ivana Gunderson
Tel: 512-279-1251
Email: igunderson@e-retina.net

Utah

University of Utah Medical Center

Salt Lake City, Utah
Paul Bernstein, MD, PhD.

Kara Halsey
Tel: 801-213-2034
Email: Kara.halsey@utah.edu

Washington

University of Washington Eye Institute

Seattle, WA
Cecilia Lee, MD

Ian Luttrell
Email: luttri@uw.edu

Francy Moses
Email: mosesf@uw.edu

Wisconsin

Medical College of Wisconsin

Milwaukee, WI USA
David Weinberg, MD

Ellie Dorsey
Tel: 414-955-7854
Email: edorsey@mcw.edu
 

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France
Hopital Lariboisiere

Paris, France
Alain Gaudric, MD

Abir Zureik
Tel: 33 1 49 95 64 86
Email: abir.zureik@aphp.fr
 

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Germany
Universitats-Augenklinik Bonn

Bonn, Germany
Frank Holz, MD

Simone Müller
Email: Simone.Mueller@ukbonn.de

Kerstin Bartsch
Email: Kerstin.Bartsch@ukbonn.de

St. Franziskus Hospital

Muenster, Germany
Prof. Daniel Pauleikhoff

Elke Attenberger
Tel: 0251-9352758
Email: elke.attenberger@uveitis-zentrum.de

Eye Center, Medical Center

Freiburg
Felicitas Bucher, MD

Dagmar Rommel
Telefon: 0761 270-40231
Email: dagmar.rommel@uniklinik-freiburg.de
 

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Israel
The Goldschleger Eye Institute

Tel Hashomer, Israel
Joseph Moisseiev, MD

Rinat Rashty
Tel: 972-3-530 2877
Email: Rinat.rashty@sheba.health.gov.il

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Switzerland

Klinik und Poliklinik fur Augenheilkunde
Inselspita
University of Bern
Bern, Switzerland
Sebastian Wolf, MD, PhD
41 31 6328503
sebastian.wolf@insel.ch

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Australia
Center for Eye Research Australia

Melbourne, Australia
Robyn Guymer, MD

Melinda Cain
Tel: 61 3 9929 8396
Email: mcain@unimelb.edu.au

Emily Caruso
Tel: 61 3 9929 8113
Email: emily.caruso@unimelb.edu.au

Lions Eye Institute

Nedlands, Australia
Ian Constable, MD

Toni Busby
Tel: +61 08 6382 0582
Email: toni.busby@lei.org.au

Diana Bowman
Tel: +61 8 9381 0777
Email: DianaBowman@lei.org.au

Save Sight Institute

Sydney NSW Australia
Mark Gillies, MD, PhD

Antoinette Dezoysa
Tel +61 2 9382 7309
Email: Antoinette.dezoysa@sydney.edu.au

Sharon McKenzie
Tel +61 2 9382 7309
Email: sharon.mckenzie@sydney.edu.au

 
 

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Netherlands
Radboud University Medical Center

Nijmegen, Netherlands

CB Hoyng, MD
Tel: +31 (0)24 36 15255
Email: trialcentrum.ohk@radboudumc.nl

Asha Kalisingh
Tel: + 0243613212
Email: asha.kalisingh@radboudumc.nl

Eramus Medical Center

Rotterdam, Netherlands
J. Vingerling, MD

Annelies Hameete
Email: a.vietje-hameete@erasmusmc.nl
 

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