Institute News

The Lowy Medical Research Institute would like to announce the latest MacTel Project Newsletter, which contains important updates on the Natural History Observation and Registry (NHOR) Study, Clinical Trials, and MacTel Projects.  This edition of the newsletter includes an update on the Phase 2 clinical trial, which was also announced in the recent press release.  It also includes information about ongoing MacTel research projects, both in the clinic and in the laboratory. We have made significant advances in our understanding of MacTel since the inception of the MacTel Project and Registry.  These advances in clinical and laboratory research would not be possible without... Read More
NT-501 Slows Progression of Disease over 24 months June 20, 2017, Cumberland, RI – Neurotech Pharmaceuticals, Inc., in collaboration with the Lowy Medical Research Institute (LMRI), today announced 24-month results demonstrating that NT-501 delivering Ciliary Neurotrophic Factor (CNTF) has a beneficial effect in patients with Macular Telangiectasia type 2 (MacTel). The multicenter, randomized clinical trial demonstrated a statistically significant reduction in the progressive loss of photoreceptors in treated versus untreated eyes. NT-501 utilizes the Company’s proprietary Encapsulated Cell Therapy (ECT) platform that can be customized to deliver specific therapeutic molecules to the back of the eye for retinal disease. The... Read More
The Lowy Medical Research Institute is helping to fund a study that will map intracellular connections in the retina.  The retina is composed of several different cell types, including neurons, glia, and blood vessels.  The retina has been studied at a sub-cellular level using electron microscopy, but these subcelluar snapshots do not provide a clear picture as to how the cells in the retina are interconnected. Read More
Two scientists affiliated with the Lowy Medical Research Institute, Dr. Peter Westenskow and Dr. Michael Dorrell, were selected to participate in a public exhibit that showcased the artistic side of science. Dr. Westenskow exhibited an image of the architecture of the retina, taken by electron microscopy. The image was taken in collaboration with Dr. Malcom Wood at The Scripps Research Institute. Read More