Author Archives for Lea Scheppke

Macular Telangiectasia Type 2: Visual Acuity, Disease End Stage, and the MacTel Area. MacTel Project Report 8.

April 21, 2020 9:51 am Published by Lea Scheppke

Tjebo F.C. Heeren, MD, Emily Y. Chew, MD, Traci Clemons, PhD, Catherine A. Egan, FRCOphth, Peter Charbel Issa, FEBO, DPhil,... View Article

Longitudinal Assessment of Remnant Foveal Cone Structure in a Case Series of Early Macular Telangiectasia Type 2

March 30, 2020 9:57 am Published by Lea Scheppke

Katie M. Litts; Mali Okada; Tjebo F. C. Heeren; Angelos Kalitzeos; Vincent Rocco; Rebecca R. Mastey; Navjit Singh; Thomas Kane;... View Article

CNTF Clinical Trials: COVID-19 Update

March 24, 2020 5:03 pm Published by Lea Scheppke

March 24, 2020 The rapid spread of COVID-19 has disrupted many standard clinical operations, including the LMRI/Neurotech Phase 1, 2,... View Article

Genetic Disruption of Serine Biosynthesis is a Key Driver of Macular Telangiectasia Type 2 Etiology and Progression

February 10, 2020 11:35 am Published by Lea Scheppke

Roberto Bonelli, Brendan R E Ansell, Luca Lotta, Thomas Scerri, Traci E Clemons, Irene Leung, The MacTel Consortium, Tunde Peto, Alan C Bird, Ferenc B Sallo, Claudia Langenberg, Melanie Bahlo. bioRxiv, Feb 10, 2020.

Phase 3 Trial Currently Enrolling MacTel Patients

December 17, 2019 12:32 pm Published by Lea Scheppke

Neurotech Pharmaceuticals, with support from the Lowy Medical Research Institute, is currently enrolling a Phase 3 clinical trial testing ciliary... View Article

Dark Adaptation in Macular Telangiectasia Type 2

November 29, 2019 10:01 am Published by Lea Scheppke

Tzaridis, Simone MD; Hess, Kristina MD; Heeren, Tjebo F. C. MD; Nadal, Jennifer; Mai, Clarissa; Herrmann, Philipp MD, PhD; Charbel... View Article

Lowy Symposium: Frontiers in Vision Research and Vascular Diseases

October 2, 2019 1:10 pm Published by Lea Scheppke

The Lowy Medical Research Institute is hosting a public scientific symposium with a focus on vision research and vascular disease.... View Article

Binocular Inhibition of Reading in Macular Telangiectasia Type 2

September 30, 2019 10:05 am Published by Lea Scheppke

Simone Tzaridis; Philipp Herrmann; Peter Charbel Issa; Simona Degli Esposti; Siegfried K Wagner; Marcus Fruttiger; Catherine Egan; Gary Rubin; Frank... View Article

The Latest MacTel Research: What does it mean for patients?

September 20, 2019 12:24 pm Published by Lea Scheppke

Scientists at the Lowy Medical Research Institute and their collaborators recently published an article describing a role for serine and... View Article

Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy

September 12, 2019 10:25 am Published by Lea Scheppke

Marin L. Gantner, Ph.D., Kevin Eade, Ph.D., Martina Wallace, Ph.D., Michal K. Handzlik, Ph.D., Regis Fallon, B.S., Jennifer Trombley, M.S.N., Roberto Bonelli, M.S., Sarah Giles, B.S., Sarah Harkins-Perry,... View Article